THANBICHLER LAB
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| WELCOME |

Bacterial Cell Biology Group

with a focus on

Chromosome segregation
Cell division
Morphogenesis
Bacterial cytoskeleton
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We study the mechanisms controlling the spatiotemporal organization of bacterial cells using a combination of
genetics, cell biology, biochemistry, biophysics, structural biology, and bioinformatics.
Our lab is located in Marburg, Germany, a beautiful historic city with more than 35 research groups working in the field of microbiology. We are associated with the Department of Biology at the University of Marburg, the Max Planck Institute for Terrestrial Microbiology, and the Center for Synthetic Microbiology (SYNMIKRO).

RECENT KEY PUBLICATIONS
The CTPase activity of ParB determines the size and dynamics of prokaryotic DNA partition complexes
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Molecular Cell
81: 3992 (2021)
Molecular architecture of the DNA-binding sites of the P-loop ATPases MipZ and ParA from Caulobacter crescentus.
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Nucleic Acids Research
48: 4869-4779 (2020)
Two-step chromosome segregation in the stalked budding bacterium Hyphomonas neptunium.
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Nature Communications
10: 3290 (2019)
ParB-type DNA segregation proteins are CTP-dependent molecular switches.
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Cell
179: 1512-1524 (2019)

FUNDING

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© M. Thanbichler 2022  │  Photos: D. Kiekebusch, W. Strobel, A. Izquierdo Martinez, Sara Jakob 
Last updated - 05 Oct 2022

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